Javascript doesn't have explicit memory mangament, it's the browser which decides when to clean it up. Sometimes it may happen that you experience unsmooth rendering of JavaScript due to a garbage collection pause.
There are many techniques that you can apply to overcome glitches caused by garbage collection (GC). More you apply more you explore. Suppose you have a game written in JavaScript , and every second you are creating a new object then its obvious that at after certain amount of time GC will occur to make further space for your application.
For real time application like games, which requires lot of space the simplest thing you can do is to reuse the same memory. It depends on you how you structure your code. If it generates lots of garbage then it might give choppy experience.